Author: IBraheem Mostafa ZA

Prof. Miski, presented at the International Symposium on the Chemistry

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There were more than 200 scientists from France, Russia, China, Uzbekistan, Kazakhstan, Iran, Algeria and Turkey attended the meeting. There were several topics discussed during the meeting including the development of medicines from natural products, and chemistry and bio-activities of natural compounds. The title Prof. Dr. Mahmud Miski was "Chemistry, Biology and Pharmacology of the Sesquiterpenes Isolated from Ferula Species Growing in Anatolia," he specifically discussed the anticancer, anti...
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Assoc Prof.Dr. Mustafa GUZEL

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Contact: [email protected] Dr. Güzel graduated from Hacettepe University School of Engineering with a B. Sc degree in Chemistry in 1987 and completed his M. Sc. and Ph. D. Degrees on Medicinal Chemistry at Clemson University, Clemson, SC in 1996 and 2001 respectively. He worked as organic lab coordinator at Northeastern University and later joined to ArQule Inc.as Sr. Synthetic Organic Chemist upon his graduation. He then joined to TransTech Pharma Inc, in High Point, NC and assumed v...
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Şükran OZDATLI, Ph. D. Student

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Contact: [email protected] She has finished her bachelor’s degree from Faculty of Pharmacy of Yeditepe University at 2013. She is currently a PhD student in Toxicology Department of Faculty of Pharmacy of Yeditepe University. She completed her graduation study with a thesis entitled “Effects of Concomitant Usage of Paracetamol and N-Acetylcysteine to Prevent Possible Paracetamol Toxicity” and also worked as Research Assistant in Yeditepe University. During this time, she studied abo...
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GRG Research Interests

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In our lab we mainly focus on drug discovery and development of various therapeutic targets such as Neurodegenerative Disorders (ALS, Alzheimer’s and Parkinson’s disease etc.), and Inflammatory Disorders (COPD, RA), GPCRs for the treatment of Diabetic Disorders (NIDDM), Cancer, Cardiovascular Disorders, Obesity, and other Metabolic Disorders.   We are also very interested in research and development with an emphasis in design and synthesis of both symmetric and asymmetric orga...
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Projects

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Novel Ghrelin Antagonists for treatment of Obesity. Novel Sigma-1 Receptor Agonists for treatment of Neurodegenerative Diseases. Novel A2A Adenosine Receptor Antagonists for the Treatment of Parkinson’s disease and SAR of the new Preladenant analogs. Discovery of novel Excitatory Amino Acid Transporter-2 (EAAT2) modulators for the treatment of ALS and other neurodegenerative disorders. Regulation of cancer cell metabolism: Targeting cancer metabolism as an alternative therapeutic trea...
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Patents & Publications

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Synthesis of Novel Methyl Jasmonate Derivatives and Evaluation of Their Biological Activity in Various Cancer Cell Lines; Bilgesu Onur Sucua, Ozgecan Savlug Ipek, Sukran Ozdatli Kurtulus, Busra Emine Yazici, Nihal Karakas, and Mustafa Guzel. Bioorganic Chemistry, (2019). DOI: https://doi.org/10.1016/j.bioorg.2019.103146 “Novel Strategies for the Synthesis of A2A Adenosine Receptor Antagonist Analogs”; Şükran Özdatlı, Hanife Pekel, Bilgesu Onur Sucu, and Mustafa Guzel; Tetrahedron Letters,...
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