INTRODUCTION to BIOMATERIALS

AIM

This course is designed to provide a general understanding of the multidisciplinary field of biomaterials. The course mainly deals with biomaterials, properties, biomedical applications, biocompatibility and biodegradability, toxicity of the materials as well as interactions at the interface of material and biological systems. Current applications of biomaterials will be evaluated to provide an understanding of material bulk and surface properties, degradation processes, various biological responses to the materials and the clinical context of their use. Course aıms to give fundamental information and perspective for student who might have different background.

CONTENT

This course contains; Introduction to Biomaterials and Types of Biomaterials,Metalic Biomaterials,Ceramic Biomaterial,Polymeric Biomaterials and Composites,Chemical Structure of Biomaterials,Physical Structure of Biomaterials,Mechanical Properties of Biomaterials,Biomaterials Degradation,Biomaterials Processing,Surface properties of Biomaterials,Surface properties of Biomaterials ,Protein Interaction with Biomaterials,Cell Interaction with Biomaterials,Tissue Response to Biomaterials.

1. 1

   Evaluate the fundamental principles of biomaterials and their properties,

   Taught by: Discussion Method, Problem Solving Method, Self Study Method, Computer-Internet Supported Instruction · Assessed by: Traditional Written Exam, Homework, Project Task

2. 2

   Classify biomaterials according to the structural properties

   Taught by: Discussion Method, Self Study Method, Question - Answer Technique, Lecture Method · Assessed by: Traditional Written Exam, Homework, Project Task

3. 3

   Uses the modern analytical techniques for characterization of biomaterials,

   Taught by: Discussion Method, Self Study Method, Question - Answer Technique, Lecture Method · Assessed by: Traditional Written Exam, Quiz

4. 4

   Evaluate interactions between biomaterials and the body

   Taught by: Discussion Method, Self Study Method, Question - Answer Technique, Lecture Method · Assessed by: Traditional Written Exam, Homework, Project Task, Quiz

5. 5

   Compare biomaterials according to the application fields

   Taught by: Discussion Method, Self Study Method, Question - Answer Technique, Lecture Method · Assessed by: Project Task, Quiz

6. 6

   Evaluates the biodegradation of biomaterials under physiological conditions

   Taught by: Discussion Method, Self Study Method, Question - Answer Technique, Lecture Method · Assessed by: Traditional Written Exam, Homework, Project Task, Quiz

7. 7

   Suggest biomaterials for a specific application

   Taught by: Discussion Method, Question - Answer Technique, Lecture Method · Assessed by: Traditional Written Exam, Homework, Project Task, Quiz

8. 8

   Suggest the most appropriate tests for biocompatibility of biomaterials

   Taught by: Discussion Method, Self Study Method, Question - Answer Technique, Lecture Method · Assessed by: Traditional Written Exam, Homework, Project Task, Quiz

9. 9

   Plan the commercialization path of a biomaterials product from laboratory to the markets

   Taught by: Discussion Method, Self Study Method, Question - Answer Technique, Lecture Method · Assessed by: Traditional Written Exam, Oral Exam, Project Task, Quiz

10. 10

    Interpret the requirements of biomaterials-blood and protein interaction

    Taught by: Discussion Method, Self Study Method, Question - Answer Technique, Lecture Method · Assessed by: Traditional Written Exam, Homework, Project Task, Quiz

WEEKLY PLAN

1. WEEK 1

   Introduction to Biomaterials and Types of Biomaterials

2. WEEK 2

   Metalic Biomaterials

   Preparation: Going through course materials

3. WEEK 3

   Ceramic Biomaterial

   Preparation: Going through course materials

4. WEEK 4

   Polymeric Biomaterials and Composites

   Preparation: Going through course materials

5. WEEK 5

   Chemical Structure of Biomaterials

   Preparation: Going through course materials

6. WEEK 6

   Physical Structure of Biomaterials

   Preparation: Going through course materials

7. WEEK 7

   Mechanical Properties of Biomaterials

   Preparation: Going through course materials

8. WEEK 8

   Biomaterials Degradation

   Preparation: Going through course materials

9. WEEK 9

   Biomaterials Processing

   Preparation: Going through course materials

10. WEEK 10

    Surface properties of Biomaterials

    Preparation: Going through course materials

11. WEEK 11

    Surface properties of Biomaterials

    Preparation: Going through course materials

12. WEEK 12

    Protein Interaction with Biomaterials

    Preparation: Going through course materials

13. WEEK 13

    Cell Interaction with Biomaterials

    Preparation: Going through course materials

14. WEEK 14

    Tissue Response to Biomaterials

    Preparation: Going through course materials

ASSESSMENT

• Rate of Midterm Exam to Success50%
• Rate of Final Exam to Success50%

WORKLOAD

READING

• Biomaterials, The intersection of Biology and Materials Science- J.S. Temenoff, A.G. Mikos, (4th edition) lecture notes and presentations
• Course presentations

TEACHING STAFF

• Prof.Dr. Yasemin YÜKSEL DURMAZCOORDINATOR
• Prof.Dr. Yasemin YÜKSEL DURMAZ